Phospho-4ebp1

WebApr 1, 2024 · We also engineered a mutant 4E-BP1 that cannot be phosphorylated by mTOR resembling de-phospho-Thr46-4E-BP1, and generated HNSCC cells expressing this mutant in a tetracycline-inducible fashion. Expression of 4E-BP1 M was sufficient to disrupt the function of the translation–initiation complex, and resulted in tumor regression in HNSCC ... WebPhospho-4E-BP1 (Ser65) Antibody detects endogenous levels of 4E-BP1 when phosphorylated at serine 65. This antibody has been shown to also recognize 4E-BP1 …

DRAM1 regulates autophagy and cell proliferation via inhibition of …

WebPhospho-4E-BP1 (Thr37/46) (236B4) Rabbit mAb detects endogenous levels of 4E-BP1 only when phosphorylated at Thr37 and/or Thr46. This antibody may cross-react with 4E-BP2 … Web实验用到的供体是Thr46(铽标记的anti-phospho-4EBP1),受体是绿色荧光标记的4EBP1,是mTOR下游信号通路的蛋白,有活性的mTOR能磷酸化4EBP1,使之与供体结合。如果mTOR活性受到抑制,供体受体距离不能达到荧光能量转移的要求,则在515nm处与485nm处的信号比值增大。 highest producer of maize in india https://aufildesnuages.com

Expression of total and phospho 4EBP1 in metastatic and …

WebPhospho-4EBP1 (Thr37, Thr46) Polyclonal Antibody Advanced Verification This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated. … WebJun 24, 2024 · Inhibition of 4EBP1 phosphorylation was sufficient to block cancer cell growth and was necessary for maximal antitumor activity. At mTORC1-selective doses, these compounds do not alter glucose... WebPhospho-4EBP1 (Thr37, Thr46) Antibody (MA5-36936) in Flow Flow cytometry of Phospho-EIF4EBP1 (Thr37, Thr46) using Jurkat cells. Samples were incubated in monoclonal Phospho-EIF4EBP1 (Thr37, Thr46) antibody ( Product # MA5-36936 ). how had okonkwo achieved fame early in life

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Phospho-4ebp1

4E-BP1 Is a Tumor Suppressor Protein Reactivated by mTOR …

WebJul 6, 2024 · 北京百奥创新科技有限公司是一家专注于生命科学的科技企业,由在国内科研试剂领域有着丰富从业经验的技术团队和管理团队组建而成,专营进口生物试剂,科学仪器,实验消耗品等。 WebPhospho-4EBP1 (Thr37, Thr46) Antibody (PA5-114544) in ICC/IF Immunocytochemistry analysis of Phospho-4EBP1 (Thr37, Thr46) in HeLa cells (heat shock treatment). Samples …

Phospho-4ebp1

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WebMar 22, 2024 · DRAM1 also dramatically downregulated the phosphorylation of both rpS6 at Ser 240/244 (Fig. 2 a and c) and 4EBP1 (Fig. 2 a and d), suggesting that the activity of p70S6K was decreased, though the phosphorylation of mTOR itself had no change (Fig. 2 a). WebDec 18, 2024 · Scoring of phospho-4EBP1 immunolabeling was performed as follows: each tumor was evaluated in a tissue microarray for positive or negative staining, and assigned a qualitative score based on whether there was low, focal staining (staining in less than 50% of the tumor cells), intermediate staining (weak staining in more than 50% of the cells ...

WebKeyTec®TR-FRET Phospho-STAT4 (Y693) Kit : KeyTec®TR-FRET Phospho-STAT5 (Y694/Y699) Kit : KeyTec®TR-FRET Total STAT5 Kit : KeyTec®TR-FRET Phospho-STAT6 … WebKeyTec®TR-FRET Phospho-STAT4 (Y693) Kit : KeyTec®TR-FRET Phospho-STAT5 (Y694/Y699) Kit : KeyTec®TR-FRET Total STAT5 Kit : KeyTec®TR-FRET Phospho-STAT6 (Y641) Kit : KeyTec®TR-FRET Total STAT6 Kit : KeyTec®TR-FRET Phospho-4EBP1 (T37/T46) Kit : KeyTec®TR-FRET Total 4EBP1 Kit : KeyTec®TR-FRET Phospho-BTK …

Web丁香通为您提供4EBP1antibod商品详情介绍:价格:询价,货号:GTX83226,CAS号:详见说明书,品牌:慧嘉生物,产地:USA,详见丁香通4EBP1antibod商品详情页; WebMay 28, 2014 · The phosphorylation status of S6RP or 4EBP1 is thus often used as a measure of mTOR activity in laboratory studies. However, whether these mTOR-associated molecules, namely AKT, mTOR, S6RP and 4EBP1, could be used as predictors of efficacy for everolimus treatment remained elusive and need further investigations.

WebPhospho-4EBP1 (Thr46) Antibody (44-1170G) in ICC/IF Immunofluorescence analysis of 4EBP1 (pT46) was done on 70% confluent log phase HeLa cells. The cells were fixed with 4% paraformaldehyde for 15 minutes, permeabilized with 0.25% Triton™ X-100 for 10 minutes, and blocked with 5% BSA for 1 hour at room temperature.

Web运动和PI3K阻断剂对大鼠骨骼肌mTOR及下游信号的作用研究,sd大鼠,大鼠阅读答案,wistar大鼠,大鼠解剖图,大鼠翻译,大鼠 蒲松龄,大鼠十二脂肠插管,大鼠固定器,大鼠代谢笼 how hack youtubeWebPhospho-4E-BP1 (Thr37/46) (236B4) Rabbit mAb detects endogenous levels of 4E-BP1 only when phosphorylated at Thr37 and/or Thr46. This antibody may cross-react with 4E-BP2 and 4E-BP3 when phosphorylated at equivalent sites. Non-specific staining has been observed in mitotic cells by immunofluorescence Phospho-4E-BP1 (Thr37/46) (236B4) Rabbit mAb how hadoop cope up with node failureWeb4EBP1 is a 118 amino acid protein with a predicted molecular weight of 13 kD. Distribution Cytosol and nucleus/ubiquitously expressed Function Regulation of global translation … highest processor speed desktopWebGeneral notes. This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility. - Improved sensitivity and specificity. - Long-term security of supply. - Animal-free production. For more information see here. how had okonkwo brought honor to his villageWebJan 9, 2012 · MPTECs were tranduced either with empty vector or NL4-3 and then incubated in media for 72 hours. Subsequently, proteins were extracted from vector/MPTECs and HIV/MPTECs, Western blots were prepared and probed for phospho-70S6K, phospho-eIF4B, and phospho-4EBP1. Immunoblots were stripped and reprobed for actin (n = 4). A. how had elie changed in a short time nightWeb山羊血小板衍生生长因子bb(pdgf-bb)elisa试剂盒 ;英文名称: pdgf-bb elisa kit ;实验名称: 山羊血小板衍生生长因子bb(pdgf-bb)elisa试剂盒 ;实验别名: 山羊血小板衍生生长因子bb(pdgf-bb)elisa试剂盒 48t/96t ;规格: 48t/96t 报价 山羊血小板衍生生长因子bb(pdgf-bb)elisa试剂盒实验目的:本试剂盒仅供研究使用 ... highest production of coffee in indiaWebJul 7, 2016 · GSK-3 differentially regulates 4EBP1 and S6RP phosphorylation in ACHN cells. a Changes in the phosphorylation levels of 4EBP1 and S6RP over time after treatment of AR-A014418 (25 μM) or rapamycin ... how hagfish produce slime