INTRODUCTION Cold agglutinin disease (CAD) is a form of acquired autoimmune hemolytic anemia (AIHA) in which cold exposure can cause clinical symptoms related to agglutination of red blood cells (RBCs) in cold parts of the body (eg, livedo reticularis or acrocyanosis) and hemolytic anemia. See more The vast majority of cold agglutinins are directed against \"I\" or \"i\" antigens of the I blood group (referred to as \"big I\" or \"little i\" … See more In certain settings, the antigen may suggest a specific infectious cause (eg, the antibodies are usually directed against I in Mycoplasma pneumoniae infection and against i in infectious … See more The big I and little i antigens are ubiquitous (present on all cell membranes) and structurally related [3-5]. Little i is the predominant … See more These complex polysaccharides also serve as precursors for the assembly of the ABO and Lewis blood group antigens. Sometimes, the … See more http://www.sciepub.com/AJMCR/abstract/13166
Hemolytic anemia in COVID-19 - PMC - National Center for …
WebOur patient’s cold agglutinin-induced hemolytic anemia diagnosis was made based on laboratory evidence of hemolysis and a positive Coomb’s test. Workups for secondary causes of AIHA such as lymphoproliferative disorders and autoimmune disease were negative. TB diagnosis was made based on the clinical and radiological findings and … WebOct 8, 2024 · headaches. cold hands and feet. pale skin. dark urine. vomiting or diarrhea. heart problems. chest pain. back or leg pain. Some of these symptoms are caused by … robot laser scanner
Increasing Incidence and Prevalence of Acquired Hemolytic …
WebJun 13, 2024 · Cold AIHA includes two types of hemolytic anemia — cold agglutinin disease and paroxysmal cold hemoglobinuria. These conditions are triggered when the antibodies bind to red blood cells at colder temperatures. Cold agglutinin disease is rare and affects 1 in every million people, with onset most often occurring between 40 and 80 … WebCold autoimmune hemolytic anemia: D5913: Mixed type autoimmune hemolytic anemia: D5919: Other autoimmune hemolytic anemia: D592: Drug-induced nonautoimmune hemolytic anemia: D594: Other nonautoimmune hemolytic anemias: D595: Paroxysmal nocturnal hemoglobinuria [Marchiafava-Micheli] D596: Hemoglobinuria due to hemolysis … WebApr 10, 2024 · Autoimmune hemolytic anemia (AIHA) and pure red cell aplasia (PRCA) are rare complications of coronavirus disease 2024 (COVID-19). ... The direct antiglobulin … robot lavavetri - glass cleaner pro