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Bmtctn-0702

WebBMT CTN 0702 Protocol Number: BMT CTN 0702 Status: Open to Accrual Title: A trial of single autologous transplant with or without consolidation therapy versus tandem autologous transplant with lenalidomide maintenance Rationale: The study compares three different treatment strategies that combine high-dose therapy and WebThe benefit of Len maintenance in patients with high risk cytogenetics remains unclear and a focus has been on increasing post transplant interventions in this group of patients. Options include consolidation, allogeneic transplant, tandem autologous transplant. We have previously reported on BMT CTN 0102 a comparison of tandem autologous versus …

Blood & Marrow Transplant Clinical Trials Network BMT CTN

WebFeb 10, 2024 · Measuring response among patients with multiple myeloma is essential for the care of patients. Deeper responses are associated with better progression free survival (PFS) and overall survival (OS). To test the hypothesis that Mass-Fix, a mass spectrometry-based means to detect monoclonal proteins, i … WebContinued, Long-Term Follow-Up and Lenalidomide Maintenance Therapy for Patients Who Have Enrolled on BMT CTN 0702 BMT CTN 0702 Long-Term Follow-Up. Learn more. … i\u0027m ahead of the game https://aufildesnuages.com

Mass-Fix better predicts for PFS and OS than standard methods

WebJan 17, 2024 · The Blood and Marrow Transplant Clinical Trials Network (BMT CTN) 0702 trial (Clinicaltrials.gov identifier: NCT01109004) was a … To compare the use of tandem autologous hematopoietic cell transplantation (AHCT) followed by lenalidomide maintenance, AHCT plus four cycles of lenalidomide, bortezomib, and dexamethasone (RVD) followed by lenalidomide, and AHCT and lenalidomide only in improving outcomes for patients with active … See more At the time of this trial, initial myeloma reductive therapy followed by high-dose melphalan plus AHCT with long-term lenalidomide was the standard of care for patients newly diagnosed with multiple myeloma (MM) in the … See more Second AHCT or RVD consolidation as post-AHCT interventions for the up-front treatment of transplantation-eligible patients with multiple myeloma did not improve progression … See more Patients with symptomatic MM who were 70 years old or younger, had a Karnofsky score equal to or greater than 70 and who received at least two … See more The BMT CTN-0702 study was a Phase III multicenter trial. All patients were randomly assigned in a 1:1:1 manner at the time of enrollment, which occurred within 7 days before the first high-dose melphalan … See more WebNov 17, 2024 · Interestingly, the StaMINA trial, which was really an extension of the BMT CTN 0702 [trial], if you remember, initially they had patients who had a single transplant [who] were then randomized to either directly going to maintenance, a second transplant, a tandem transplant and then maintenance, or 4 cycles of VRd [bortezomib (Velcade ... i\u0027m a hedgehog not a cat

How I treat high-risk multiple myeloma Blood - American Society …

Category:CPT ® 90702 in section: Diphtheria, tetanus toxoids vaccine - Find …

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Bmtctn-0702

BMT CTN Protocol Listing BMT CTN

WebFeb 10, 2024 · Follow-up information was based on BMT CTN 0702 and on the subsequent follow-up study, BMT CTN 07LT to derive long-term follow-up [10, 13]. PFS was … Web93702, Under Non-invasive Physiologic Studies and Procedures. The Current Procedural Terminology (CPT ®) code 93702 as maintained by American Medical Association, is a …

Bmtctn-0702

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Webevent definition in the BMT CTN 0702 study was modified to focus mainly on disease progression and not disease relapse, by defining a minimal burden of disease as the threshold for defining progression in patients previously in CR. The protocol separates the definition of progression according to prior best responses, i.e. prior CR or not. WebMay 25, 2024 · Methods: 07LT was offered to pts who were progression-free at 38 mo; completed planned Len maintenance and were within 4 years of BMT CTN 0702 follow …

WebNorthside Hospital was also the only center in the country (out of 175) in 2024 to maintain outcomes in the “above expected” range for 14 consecutive reporting years.*. For more … WebBMT CTN 0702 Protocol Number: BMT CTN 0702 Status: Open to Accrual Title: A trial of single autologous transplant with or without consolidation therapy versus tandem …

WebThis study is designed to compare long-term outcomes among patients randomized on the BMT CTN 0702 protocol (NCT01109004), "A Trial of Single Autologous Transplant with or without Consolidation Therapy versus Tandem Autologous Transplant with Lenalidomide Maintenance for Patients with Multiple Myeloma". It is hypothesized that use of novel anti ... WebTherapy for Patients Who Have Enrolled on BMT CTN 0702.” 1. General Review of Study Design and Process 1.1 Study Objectives BMT CTN protocol 07LT is a follow-up study to BMT CTN 0702, which was a Phase 3, multi-center trial designed to compare progression-free survival and additional outcomes between

WebMar 1, 2024 · PRIMeR is the first U.S.-based ancillary study of MRD assessment by multiparameter flow cytometry (MFC). Patients were enrolled on a national 3-arm RCT (BMT CTN 0702, STAMiNA trial, ClinicalTrials.gov Identifier: NCT01109004) comparing 1) tandem auto-HCT, 2) single auto-HCT and 3) single auto-HCT, 4 cycles of lenalidomide, …

WebFeb 19, 2024 · CPT ® Code Set. 90702 - CPT® Code in category: Diphtheria, tetanus toxoids vaccine. CPT Code information is available to subscribers and includes the CPT … netl fact sheetWebMay 12, 2024 · Long-term follow-up of BMT CTN 0702 (STaMINA) of postautologous hematopoietic cell transplantation (autoHCT) strategies in the upfront treatment of multiple myeloma (MM) [abstract]. J Clin Oncol. 2024; 38 (suppl 15). Abstract 8506. i\u0027m a hero for funWebContinued, Long-Term Follow-Up and Lenalidomide Maintenance Therapy for Patients Who Have Enrolled on BMT CTN 0702 BMT CTN 0702 Long-Term Follow-Up. Learn more. DISEASE GROUP: Transplant. current phase: NA. STUDY STATUS: Accepting Patients. Location: Hackensack, NJ. For More information: Call 201-518-3587. Explore. i\u0027m a hero streamingWebMethods: 07LT was offered to pts who were progression-free at 38 mo; completed planned Len maintenance and were within 4 years of BMT CTN 0702 follow up. Among 431 07LT eligible patients, 273 enrolled and 179 opted to continue maintenance until … netley view soton water ship spottingWebDec 23, 2014 · Lenalidomide: In BMT CTN 0702, maintenance therapy with lenalidomide started at 10 mg daily for three months and increased to 15 mg daily. The duration of maintenance was three years in all treatment arms. Lenalidomide will be administered initially at the patient's last documented dose prior to discontinuation of BMT CTN 0702 … i\u0027m a hero songWebDec 2, 2024 · The BMT CTN 0702 was supported by Grant No. U10HL069294 to the Blood and Marrow Transplant Clinical Trials Network from the National Heart, Lung, and Blood Institute and the National Cancer ... netl githubWebMay 12, 2024 · Survival of multiple myeloma (MM) has significantly improved over the past decade; however, a composed group of patients (15% to 20%), named high-risk (HR) MM, still experiences reduced survival. Both tumor biology and suboptimal/absent responses to therapy may underlie HR definition and a clear uniform identification of risk factors is … netl grants and solicitations